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AOD-9604 Peptide

Buy AOD-9604 Peptide Pakistan Online From Direct Sarms

AOD-9604 is a peptide originally developed to aid in fat metabolism and enhance weight loss, offering potential benefits such as improved body composition, reduced body fat, and support for metabolic health without significant adverse effects.

What is AOD-9604?

AOD-9604 is a synthetic peptide derived from the C-terminal part of human growth hormone (HGH). Unlike HGH, AOD-9604 is designed to focus on fat metabolism and weight management without causing the anabolic growth effects linked to HGH.

This modified amino acid sequence works by mimicking the fat-burning effects of natural growth hormone, targeting stored fat for energy. Clinical trials have studied its effectiveness for weight loss and its potential to improve metabolic health. Administered through injections, it is gaining attention for helping manage body composition with minimal risk of side effects.

How Does AOD-9604 Work?

AOD-9604 works by activating the pituitary gland to promote lipolysis, the breakdown of stored fat, while simultaneously suppressing lipogenesis, the creation of new fat. This peptide mimics the activity of the natural growth hormone’s fat-reducing domain, targeting adipose tissue to promote the breakdown of stored fat and its conversion into energy.

Importantly, the peptide achieves these effects without influencing blood sugar levels or promoting muscle growth, which sets it apart from the complete human growth hormone. By acting on fat metabolism pathways, it supports weight management and assists in improving overall metabolic health. This targeted action makes it an appealing option for individuals aiming to reduce body fat without the broader hormonal impacts often associated with HGH therapies.

 AOD-9604 Specifications

Molecular Formula: C78H123N23O23S2

Molecular Weight: 1815.1 g/mol

Sequence: H-Tyr-Leu-Arg-Ile-Val-Gln-Cys(1)-Arg-Ser-Val-Glu-Gly-Ser-Cys(1)-Gly-Phe-OH

View our AOD-9604 High-Performance Liquid Chromatography (HPLC) Certificate here.

AOD-9604 Structure
Source: PubChem

What are the suggested research benefits of AOD-9604 Peptide?

  • Fat Reduction and Weight Loss: One of the most studied benefits is its ability to promote fat loss. A Pakistan study demonstrated that it promotes lipolysis (fat breakdown) and inhibits lipogenesis (fat creation). This is significant because it was shown to help reduce fat in animal models without influencing insulin or blood glucose levels, suggesting a potential benefit for individuals looking to reduce fat without the side effects associated with other weight loss drugs [1]. 
    Another study conducted on human subjects found that it effectively reduced abdominal fat when administered daily. This was demonstrated through changes in body fat percentage and waist-to-hip ratio, which are important indicators of central adiposity [2].
  • Improved Metabolism: It may improve metabolic function by enhancing the breakdown of fats and increasing the oxidation of fatty acids. In a Pakistan study using animal models, peptide administration resulted in increased metabolic rates and improved overall energy expenditure. This is potentially beneficial for individuals with metabolic disorders or those aiming to maintain a healthier body composition [3].
  • Anti-Aging and Muscle Preservation: Although not as extensively researched as fat loss, there are indications that it may also have anti-aging effects, primarily through its ability to promote a leaner body composition and prevent muscle loss [4]. Some Pakistan studies have explored the relationship between AOD and its impact on muscle mass preservation, suggesting that it may help prevent the catabolism (breakdown) of muscle tissue, which often occurs with aging.
    A small study in elderly patients found that AOD-9604 appeared to maintain muscle strength and function, potentially mitigating the effects of sarcopenia (age-related muscle loss) [5].
  • Joint and Cartilage Health: Some Pakistan research suggests that it may offer benefits for joint health, potentially aiding in cartilage repair. In animal models, peptide administration was shown to have positive effects on the cartilage of joints, which may be beneficial in conditions like osteoarthritis [5]. Although clinical studies in humans are limited, the peptide’s role in promoting cartilage repair has shown promise in preclinical studies.
  • Safety and Tolerability: It is generally considered safe when compared to other forms of growth hormone therapy, such as recombinant HGH. It does not appear to influence blood sugar levels or cause the insulin resistance commonly associated with HGH use. A study investigating the safety profile of AOD in human subjects found that it was well-tolerated with minimal side effects, making it an attractive option for weight management and anti-aging treatments [6].

What AOD-9604 products are available?

Buy AOD-9604 BPC-157 Nasal Stack

Buy BPC-157 and AOD-9604 Peptide StackBuy AOD-9604 BPC-157 peptide stack Pakistan for clinical research from Direct Sarms.

Buy AOD-9604 Nasal Spray

AOD-9604 Nasal Spray 15mlBuy AOD-9604 nasal spray Pakistan for research from Direct Sarms. 

Frequently Asked Questions (FAQ’s) about AOD-9604 Peptides

Buy AOD-9604 Peptide
Image of a fat cell and silhouette of an obese person and thin person

Is AOD-9604 legal?

It is legally available in some regions; however, its legality depends on the specific regulations of the country in question. It is important to note that it has not been approved by the FDA for use in humans, which means it is not legally classified as a medication in the United States. Individuals considering its use should consult local laws and seek guidance from a medical professional.

Can AOD-9604 promote muscle growth?

It is not designed to promote muscle growth. Its primary function revolves around fat metabolism and weight management, differing from traditional HGH-based growth peptides.

Are there any side effects associated with AOD-9604?

Potential side effects are minimal but may include localised irritation at the injection site or mild gastrointestinal discomfort. Always consult a professional healthcare provider before commencing any clinical trials.

How safe is AOD-9604?

In six clinical trials, it showed no impact on IGF-1 levels, no adverse effects on carbohydrate metabolism, and no immunogenicity. No serious side effects or withdrawals were reported. Overall, it exhibited a safety and tolerability profile comparable to placebo.

How does AOD-9604 compare to HGH?

Research explored the effects of human growth hormone (hGH) and AOD9604 on weight, fat oxidation, and energy balance in obese and lean mice. Both reduced body weight gain and increased fat oxidation in obese mice, but AOD also promoted fat breakdown without affecting blood sugar or insulin levels. Unlike hGH, AOD does not bind to hGH receptors or trigger cell growth, suggesting it works through different pathways.

Does AOD-9604 suppress appetite?

It primarily targets fat metabolism and body composition but lacks clinical evidence to show it directly suppresses appetite like other weight managment options. Its benefits are focused on fat-burning rather than appetite control.

Further Reading

For more information, explore our latest blog posts dedicated to AOD-9604 peptides.

Buy AOD-9604 Peptides Today!

Buy AOD-9604 peptide Pakistan from Direct Sarms, your reliable source for 99% pure research-grade peptides. It’s available in multiple formats, including lyophilized powder (2mg, 5mg, and 10mg vials), 15ml and 30ml nasal sprays, and 2mg pre-mixed pens for added convenience. Designed for laboratory use, AOD-9604 offers exceptional purity and quality to deliver accurate and reliable research results.

Direct Sarms ensures high-quality peptides with precise dosing and reliable results, prioritizing care and consistency for your research needs.


Scientific References

[1] M Heffernan, R J Summers, A Thorburn, E Ogru, et al (2001) The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice – Endocrinology, 2001 Dec, Volume 142 (Issue 12), Pages 5182-9.

[2] M A Heffernan, A W Thorburn, B Fam, R Summers, et al (2001) Increase of fat oxidation and weight loss in obese mice caused by chronic treatment with human growth hormone or a modified C-terminal fragment – International Journal of Obesity Related Metabolism Disorders, 2001 Oct, Volume 25 (Issue 10), Pages 1442-9.

[3] F M Ng, J Sun, L Sharma, R Libinaka, W J Jiang, and R Gianello (2000) Metabolic studies of a synthetic lipolytic domain (AOD9604) of human growth hormone – Hormone Research, 2000, Volume 53 (Issue 6), Pages 274-8.

[4] Monika Misra (2013) Obesity Pharmacotherapy: Current Perspectives and Future Directions – Current Cardiology Reviews, 2013 Feb, Volume 9 (Issue 1), Pages 33–54.

[5] Dong Rak Kwon and Gi Young Park (2015) Effect of Intra-articular Injection of AOD9604 with or without Hyaluronic Acid in Rabbit Osteoarthritis Model – Annals of Clinical and Laboratory Science, 2015 Summer, Volume 45 (Issues 4), Pages 426-32.

[6] Heike Stier, Evert Vos, David Kenley (2013) Safety and Tolerability of the Hexadecapeptide AOD9604 in Humans – Journal of Endocrinology and Metabolism, 2013, Volume 3 (Issue 1-2), Pages 7-15.


ALL CONTENT AND PRODUCT INFORMATION AVAILABLE ON THIS WEBSITE IS FOR EDUCATIONAL PURPOSES ONLY.

DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Direct Sarms website is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.